To Determine the Frequency of Hypomagnesemia among patients with Acute Ischemic Stroke and to Study the Correlation of Serum Magnesium with Modified Rankin Scale After Acute Ischemic Stroke

Aim: The objective of this study is. “To determine the frequency of hypomagnesemia among patients with acute ischemic stroke and to study the correlation of serum magnesium with Modified Rankin Scale after acute ischemic stroke.” Study design: It is a cross sectional study. Setting: Indoor patients, departments of Medicine, Mayo Hospital, Lahore Duration of study:Six months from “15 th May 2014 to 15 th November 2014” Methodology:200 patients with acute ischemic stroke fulfilling the inclusion criteria were selected. 2ml venous sample for serum magnesium level was taken 1 st 6 hour of stroke. Presence or absence of hypomagnesemia in patients after acute ischemic stroke was recorded during hospital stay of patients, receiving standard management protocol of ischemic stroke. The correlation co-efficient of serum magnesium level with Modified Rankin Scale was calculated through SPSS-17 as Pearson Correlation. P< 0.05 was taken as significant. Results:The mean age of patients was 52.65+10.66 years. There were 134(67%) male while 66(33%) were females. The maletofemale ratio was 2.03:1. The mean magnesium level in all the patients was measured as 1.71+0.51mg/dl. Hypomagnesemia was found in 32% of patients. The mean MRS score in all the patients was measured as 3.22+1.27. In this study, the correlation coefficient between magnesium level and MRS score was found as r= 0.674 which showed negative relationship between magnesium and MRS. Conclusion: It was concluded through the results of this study that low levels of magnesium in the body can cause more severe stroke as relationship is strong between low magnesium level and severity of stroke.